Dr. Seeger is Professor of Pediatrics in the Keck School of Medicine, Director of Cancer Research Program of The Saban Research Institute, and Division Head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Childrens Hospital Los Angeles whose expertise includes pre-clinical immunotherapy, biomarker development and application and early phase clinical trials. Currently, he is the Principal Investigator of a PPG, an R01, an R33, and two U10s. Dr. Seegers therapeutic research deals with immunotherapy strategies that seek to maximize natural killer (NK) cell activity with tumor cell targeting antibodies and with agents that modify the tumor microenvironment milieu to minimize NK suppressive effects of monocytes/macrophages producing IL-6 and TGFss1. His biomarker research, in collaboration with Dr. Shahab Asgharzadeh, has resulted in a 14-gene expression signature (TaqMan(r) Low Density Array, TLDA) that predicts outcome for children with high-risk metastatic neuroblastoma. He also has developed a second TLDA assay that quantifies expression of five neuroblastoma genes in bone marrow and blood with the ability to detect 1 tumor cell/million normal cells. This assay is proving useful for monitoring response and predicting outcome. As Principal Investigator of an NCI-funded Neuroblastoma PPG, he Co-Chairs the Scientific Review Committee of the New Approaches to Neuroblastoma Therapy consortium (see www.nant.org), which sets directions and reviews clinical trial proposals. NANT is an early-phase clinical trials consortium of 15 institutions in North America that tests new treatments, biomarkers, and imaging for children with refractory or recurrent neuroblastoma.
Dr. Robert Charles Seeger, MD
- Pediatric Hematology-Oncology
- Childrens Hospital Los Angeles 4650 W Sunset Blvd, Los Angeles, CA 90027
- (323) 361-6177
Brief Intro
View More
Education Background
RESIDENCY
Fairview University Medical Center
Languages Spoken
- Spanish
- English
Location & Hours
- Childrens Hospital Los Angeles
- 4650 W Sunset Blvd, Los Angeles, CA 90027
Specialties Treated
- Pediatric Hematology-Oncology
Similar Doctors Nearby
-
View ProfilesDr. Mohamad Shaheedy- Oncology, Pediatric Hematology-Oncology, Pediatrics
- 68 years of experience
- Los Angeles, CA
-
View ProfilesDr. Robert L Baehner
- Oncology, Pediatric Hematology-Oncology, Pediatrics
- 65 years of experience
- Los Angeles, CA
-
View ProfilesDr. Stephen Arthur Feig
- Pediatric Hematology-Oncology, Pediatrics
- 62 years of experience
- Los Angeles, CA
-
View ProfilesDr. Stuart Elliott Siegel
- Pediatric Hematology-Oncology
- 58 years of experience
- Los Angeles, CA
-
View ProfilesDr. John Joseph Quinn
- Oncology, Pediatric Hematology-Oncology
- 57 years of experience
- Los Angeles, CA
-
View ProfilesDr. Angela Wendy Miser
- Hematology, Oncology, Pediatric Hematology-Oncology
- 54 years of experience
- Los Angeles, CA
-
View ProfilesDr. Sun Hi Lee
- Oncology, Pediatric Hematology-Oncology, Pediatrics
- 54 years of experience
- Los Angeles, CA
-
View ProfilesDr. Sung Jeen Hong
- Adolescent Medicine, Oncology, Pediatric Hematology-Oncology, Pediatrics
- 54 years of experience
- Los Angeles, CA
CA Hospitals by Specialty
- Cancer 86
- Cardiology, Heart & Vascular Surgery 79
- Orthopedics 161
- Neurology & Neurosurgery 120
- Gastroenterology & GI Surgery 149
- Pulmonology & Lung Surgery 161
- Diabetes & Endocrinology 65
- Children's Hospital 18
- Urology 149
- Psychiatry 91
- Geriatrics 143
- Rehabilitation 73
- Obsterics & Gynecology 23
- Ophthalmology 8
- Ear, Nose & Throat 10
- Rheumatology 4
- Long Term Care 19
- Maternity Care (Uncomplicated Pregnancy) 99